Exercise and Education Versus Saline Injections for Knee Osteoarthritis: An Equivalence Trial (ptinquest.libsyn.com)

• Exercise and education non-inferior to saline injections.
• Primary endpoint: pain at 12 months (KOOS).
• Supports exercise as first-line treatment for knee osteoarthritis.

"A randomized controlled equivalence trial compared exercise and education versus saline injections for knee osteoarthritis. At 12 months, pain reduction was similar between groups, with conservative therapy proving non-inferior. The study supports exercise therapy as first-line treatment and questions the benefit of saline injections."